Vrabel’s return to Tennessee adds an emotional edge as the Titans host New England, with McCoy steering an interim attack and Simmons looming as a disruptive interior force. New England’s run game has cratered, forcing the offense to lean on play-action and May’s arm while Tennessee pins its hopes on time of possession and a stingy defense.

Key matchup: Simmons versus the Patriots’ interior line could decide drives early, while Landry’s edge presence (when healthy) could swing field position. For fantasy, expect Titans’ grinders to benefit if they control the clock, and Patriots pass-catchers to rely on big plays against a secondary capable of giving up chunk plays.